Biofísica y Biotecnología Molecular
Listado de producción del grupo
Datos obtenidos de UGR y plataforma SICA2
Listando 373 resultados
| Titulo | Año | Tipo |
|---|---|---|
Conformational Stabilization of Gp41-Mimetic Miniproteins Opens Up New Ways of Inhibiting HIV-1 Fusion
FRANCISCO CONEJERO LARA
|
2022 | Articulo |
Understanding binding affinity and specificity of modular protein domains: A focus in ligand design for the polyproline-binding families
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER RUIZ SANZ, JAVIER MURCIANO CALLES
|
2022 | Capítulo de libro |
Gallic acid: a natural compound exerting antitumoral activity via interaction with G-quadruplexes
MIGUEL SORIANO RODRIGUEZ, JOSÉ GUTIÉRREZ FERNÁNDEZ, MARTA EUGENIA CUADROS CELORRIO, JAVIER MURCIANO CALLES, INMACULADA RAMÍREZ MACÍAS, Victoria Sánchez Martín, Ana del Carmen Soriano Lerma
|
2022 | Articulo en prensa |
A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation
ANGEL LUIS PEY RODRÍGUEZ, Juan Luis Pacheco García
|
2022 | Articulo |
New salicylic acid derivatives, double inhibitors of glycolate oxidase and lactate dehydrogenase, as effective agents decreasing oxalate production
FRANCISCO FRANCO MONTALBÁN, JOSÉ ANTONIO GÓMEZ VIDAL, MÓNICA DÍAZ GAVILÁN, ANGEL LUIS PEY RODRÍGUEZ
|
2022 | Articulo |
Targeting HIF-1¿ Function in Cancer through the Chaperone Action of NQO1: Implications of Genetic Diversity of NQO1
ANGEL LUIS PEY RODRÍGUEZ, Juan Luis Pacheco García, ROGELIO JESÚS PALOMINO MORALES
|
2022 | Review |
Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity-Making Mutations
ANGEL LUIS PEY RODRÍGUEZ, Juan Luis Pacheco García, ROGELIO JESÚS PALOMINO MORALES
|
2022 | Articulo |
Proteomic approaches for untangling pharmacological targets in acute myeloid leukemia
Maria del Carmen Hernandez Valladares
|
2022 | Review |
The chromatin-regulating CoREST complex is animal specific and essential for development in the cnidarian Nematostella vectensis
Maria del Carmen Hernandez Valladares
|
2022 | Articulo |
Comparing efficiency of lysis buffer solutions and sample preparation methods for liquid chromatography-mass spectrometry analysis of human cells and plasma
Maria del Carmen Hernandez Valladares
|
2022 | Articulo |
Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme
ANGEL LUIS PEY RODRÍGUEZ, Juan Luis Pacheco García
|
2022 | Articulo |
Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core
ANGEL LUIS PEY RODRÍGUEZ, Juan Luis Pacheco García
|
2022 | Articulo |
Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations
ROGELIO JESÚS PALOMINO MORALES, ANGEL LUIS PEY RODRÍGUEZ, Juan Luis Pacheco García
|
2022 | Articulo |
Effect of naturally-occurring mutations on the stability and function of cancer-associated NQO1: Comparison of experiments and computation
ANGEL LUIS PEY RODRÍGUEZ, Juan Luis Pacheco García
|
2022 | Articulo |
In situ real-time monitoring the mechanism of selfassembly of short peptide supramolecular polymers
FRANCISCO CONEJERO LARA, LUIS ALVAREZ DE CIENFUEGOS RODRIGUEZ, JUAN MANUEL CUERVA CARVAJAL, ANGEL ORTE GUTIERREZ, MODESTO TORCUATO LÓPEZ LÓPEZ, CRISTINA GILA VILCHEZ, JUAN ANTONIO GONZÁLEZ VERA
|
2021 | Articulo |
Insulin Crystals Grown in Short-Peptide Supramolecular Hydrogels Show Enhanced Thermal Stability and Slower Release Profile
FERMÍN SÁNCHEZ DE MEDINA LÓPEZ-HUERTAS, FRANCISCO CONEJERO LARA, LUIS ALVAREZ DE CIENFUEGOS RODRIGUEZ, OLGA MARTINEZ AUGUSTIN, MODESTO TORCUATO LÓPEZ LÓPEZ, Rafael Contreras Montoya, Mari Carmen Mañas Torres
|
2021 | Articulo |
Extremely Thermostabilizing Core Mutations in Coiled-Coil Mimetic Proteins of HIV-1 gp41 Produce Diverse Effects on Target Binding but Do Not Affect Their Inhibitory Activity
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2021 | Articulo |
Insights into the co-assemblies formed by different aromatic short-peptide amphiphiles
FRANCISCO CONEJERO LARA, FRANCISCO FRANCO MONTALBÁN, JUAN ANTONIO TAMAYO TORRES, LUIS ALVAREZ DE CIENFUEGOS RODRIGUEZ, JUAN MANUEL CUERVA CARVAJAL, ANGEL ORTE GUTIERREZ, MODESTO TORCUATO LÓPEZ LÓPEZ, CRISTINA GILA VILCHEZ, Mari Carmen Mañas Torres, JUAN ANTONIO GONZÁLEZ VERA
|
2021 | Articulo |
Conformational flexibility of the conserved hydrophobic pocket of HIV-1 gp41. Implications for the discovery of small-molecule fusion inhibitors
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2021 | Articulo |
Rapid Conversion of Amyloid-Beta 1-40 Oligomers to Mature Fibrils through a Self-Catalytic Bimolecular Process
FRANCISCO CONEJERO LARA, MARIA PAZ CARRASCO JIMENEZ, BERTRAND MOREL
|
2021 | Articulo |
The FDA-Approved Antiviral Raltegravir Inhibits Fascin1-Dependent Invasion of Colorectal Tumor Cells In Vitro and In Vivo
JAVIER RUIZ SANZ
|
2021 | Articulo |
Intrinsically disordered protein NUPR1 binds to the armadillo-repeat domain of Plakophilin 1
MARIA ESTHER FAREZ VIDAL, ANGEL LUIS PEY RODRÍGUEZ
|
2021 | Articulo |
Dimerization Drives Proper Folding of Human Alanine:Glyoxylate Aminotransferase But Is Dispensable for Peroxisomal Targeting
ANGEL LUIS PEY RODRÍGUEZ
|
2021 | Articulo |
Galactosemia: Towards Pharmacological Chaperones
ANGEL LUIS PEY RODRÍGUEZ
|
2021 | Review |
Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue
ANGEL LUIS PEY RODRÍGUEZ, ROGELIO JESÚS PALOMINO MORALES
|
2021 | Articulo |
Effects of the autophagy-inhibiting agent chloroquine on acute myeloid leukemia cells: characterization of patient heterogeneity
Maria del Carmen Hernandez Valladares
|
2021 | Articulo |
Therapeutic use of valproic acid and all-trans retinoic acid in acute myeloid leukemia-literature review and discussion of possible use in relapse after allogeneic stem cell transplantation
Maria del Carmen Hernandez Valladares
|
2021 | Review |
Patient heterogeneity in acute myeloid leukemia: leukemic cell communication by release of soluble mediators and its effects on mesenchymal stem cells
Maria del Carmen Hernandez Valladares
|
2021 | Articulo |
Proteomic studies of primary acute myeloid leukemia cells derived from patients before and during disease-stabilizing treatments based on all-trans retinoic acid and valproic acid
Maria del Carmen Hernandez Valladares
|
2021 | Articulo |
Proteomic Characterization of Spontaneous Stress-Induced In Vitro Apoptosis of Human Acute Myeloid Leukemia Cells; Focus on Patient Heterogeneity and Endoplasmic Reticulum Stress
Maria del Carmen Hernandez Valladares
|
2021 | Articulo |
Proteomic comparison of bone marrow derived osteoblasts and mesenchymal stem cells
Maria del Carmen Hernandez Valladares
|
2021 | Articulo |
Caracterización termodinámica y estructural de inhibidores proteicos del VIH-1 dirigidos contra gp41
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2020 | Tesis Doctoral |
Molecular mechanisms of amyloid aggregation in human proteinopathies
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2020 | Capítulo de libro |
Thermodynamic dissection of the interface between HIV-1 gp41 heptad repeats reveals cooperative interactions and allosteric effects
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2020 | Articulo |
Probing Vulnerability of the gp41 C-Terminal Heptad Repeat as Target for Miniprotein HIV Inhibitors
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2020 | Articulo |
PDZ/PDZ interaction between PSD-95 and nNOS neuronal proteins: A thermodynamic analysis of the PSD95-PDZ2/nNOS-PDZ interaction
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER MURCIANO CALLES
|
2020 | Articulo |
The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c¿Src tyrosine kinase
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2020 | Articulo |
thermodynamic analysis of point mutations inhibiting high-temperature reversible oligomerization of PDZ3
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2020 | Articulo |
Lysozyme crystals dyed with bromophenol blue: where has the dye gone?
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2020 | Articulo |
Stability, conformational plasticity, oligomerization behaviour and equilibrium unfolding intermediates of the Ebola virus matrix protein VP40
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER RUIZ SANZ
|
2020 | Letters |
New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells
JAVIER RUIZ SANZ
|
2020 | Articulo |
Comprehensive biophysical and functional study of ziv-aflibercept: characterization and forced degradation
SALVADOR CASARES ATIENZA, NATALIA NAVAS IGLESIAS
|
2020 | Articulo |
BANK1 interacts with TRAF6 and MyD88 in innate immune signaling in B cells
ANGEL LUIS PEY RODRÍGUEZ
|
2020 | Articulo |
Naturally-Occurring Rare Mutations Cause Mild to Catastrophic Effects in the Multifunctional and Cancer-Associated NQO1 Protein
ANGEL LUIS PEY RODRÍGUEZ, Juan Luis Pacheco García
|
2020 | Articulo |
The Catalytic Cycle of the Antioxidant and Cancer-Associated Human NQO1 Enzyme: Hydride Transfer, Conformational Dynamics and Functional Cooperativity
ANGEL LUIS PEY RODRÍGUEZ
|
2020 | Articulo |
Towards Accurate Genotype-Phenotype Correlations in the CYP2D6 Gene
ANGEL LUIS PEY RODRÍGUEZ
|
2020 | Editorial |
Biological characteristics of aging in human acute myeloid leukemia cells: the possible importance of aldehyde dehydrogenase, the cytoskeleton and altered transcriptional regulation
Maria del Carmen Hernandez Valladares
|
2020 | Articulo |
The implementation of mass spectrometry-based proteomics workflows in clinical routines of acute myeloid leukemia: applicability and perspectives
Maria del Carmen Hernandez Valladares
|
2020 | Review |
Proteome and phosphoproteome changes associated with prognosis in acute myeloid leukemia
Maria del Carmen Hernandez Valladares
|
2020 | Articulo |
The progression of acute myeloid leukemia from first diagnosis to chemoresistant relapse: a comparison fo proteomic and phosphoproteomic profiles
Maria del Carmen Hernandez Valladares
|
2020 | Articulo |
Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2019 | Articulo |
Early mechanisms of amyloid fibril nucleation in model and disease-related proteins
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2019 | Book-Review |
Ultrafast folding kinetics of WW domains reveal how the amino acid sequence determines the speed limit to protein folding
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2019 | Articulo |
Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER MURCIANO CALLES
|
2019 | Articulo |
Protein conservation method affects MamC-mediated biomineralization of magnetic nanoparticles
SALVADOR CASARES ATIENZA, CONCEPCION JIMENEZ LOPEZ, ANA ISABEL AZUAGA FORTES, Ylenia María Jabalera Ruz, MARÍA ANTONIA FERNÁNDEZ VIVAS
|
2019 | Articulo |
Tuning properties of biomimetic magnetic nanoparticles by combining magnetosome associated proteins
SALVADOR CASARES ATIENZA, CONCEPCION JIMENEZ LOPEZ, ANA ISABEL AZUAGA FORTES, Ylenia María Jabalera Ruz, MARÍA ANTONIA FERNÁNDEZ VIVAS
|
2019 | Articulo |
Structure-Function of MamC loop and its effect on the In Vitro Precipitation of Biomimetic Magnetite Nanoparticles
SALVADOR CASARES ATIENZA, CONCEPCION JIMENEZ LOPEZ, ANA ISABEL AZUAGA FORTES, Ylenia María Jabalera Ruz, MARÍA ANTONIA FERNÁNDEZ VIVAS
|
2019 | Articulo |
Comparative stability studies of different infliximab and biosimilar CT-P13 clinical solutions by combined use of physicochemical analytical techniques and Enzyme-Linked Immunosorbent Assay ELISA
LUIS CUADROS RODRÍGUEZ, SALVADOR CASARES ATIENZA, NATALIA NAVAS IGLESIAS
|
2019 | Articulo |
The p12 subunit of human polymerase ¿ uses an atypical PIP-box for molecular recognition of proliferating cell nuclear antigen (PCNA)
JAVIER MURCIANO CALLES
|
2019 | Articulo |
Double Monoubiquitination Modifies the Molecular Recognition Properties of p15PAF Promoting Binding to the Reader Module of Dnmt1
JAVIER MURCIANO CALLES
|
2019 | Articulo |
Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses
ANGEL LUIS PEY RODRÍGUEZ
|
2019 | Articulo |
Structural and functional insights on the roles of molecular chaperones in the mistargeting and aggregation phenotypes associated with primary hyperoxaluria type I.
ANGEL LUIS PEY RODRÍGUEZ
|
2019 | Articulo |
Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability
ANGEL LUIS PEY RODRÍGUEZ, Rubén Martín Escolano, Juan Luis Pacheco García
|
2019 | Articulo |
NAD(P)H quinone oxidoreductase (NQO1): an enzyme which needs just enough mobility, in just the right places.
ANGEL LUIS PEY RODRÍGUEZ
|
2019 | Book-Review |
Systemic Alanine Glyoxylate Aminotransferase mRNA Improves Glyoxylate Metabolism in a Mouse Model of Primary Hyperoxaluria Type 1.
ANGEL LUIS PEY RODRÍGUEZ
|
2019 | Articulo |
Anion-specific interaction with human NQO1 inhibits flavin binding
ANGEL LUIS PEY RODRÍGUEZ
|
2019 | Articulo |
A Dynamic Core in Human NQO1 Controls the Functional and Stability Effects of Ligand Binding and Their Communication across the Enzyme Dimer
ANGEL LUIS PEY RODRÍGUEZ
|
2019 | Articulo |
Warfarin increases thermal resistance of albumin through stabilization of the protein lobe that includes its binding site
ANGEL LUIS PEY RODRÍGUEZ
|
2019 | Articulo |
NQO1: A target for the treatment of cancer and neurological diseases, and a model to understand loss of function disease mechanisms
ANGEL LUIS PEY RODRÍGUEZ
|
2019 | Book-Review |
Protein Post-Translational Modification Crosstalk in Acute Myeloid Leukemia Calls for Action
Maria del Carmen Hernandez Valladares
|
2019 | Review |
The Capacity of Long-Term in Vitro Proliferation of Acute Myeloid Leukemia Cells Supported Only by Exogenous Cytokines Is Associated with a Patient Subset with Adverse Outcome
Maria del Carmen Hernandez Valladares
|
2019 | Articulo |
Effects of insulin and pathway inhibitors on the PI3K-Akt-mTOR phosphorylation profile in acute myeloid leukemia cells
Maria del Carmen Hernandez Valladares
|
2019 | Articulo |
Biocalorimetry: differential scanning calorimetry of protein solutions
FRANCISCO CONEJERO LARA, JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER RUIZ SANZ, ANA ISABEL AZUAGA FORTES
|
2018 | Capítulo de libro |
Dynamic micellar oligomers of amyloid beta peptides play a crucial role in their aggregation mechanisms
FRANCISCO CONEJERO LARA, CARMEN MARCO DE LA CALLE, MARIA PAZ CARRASCO JIMENEZ, BERTRAND MOREL
|
2018 | Articulo |
Global Protein Stabilization Does Not Suffice to Prevent Amyloid Fibril Formation
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2018 | Articulo |
Approaching the thermodynamic view of protein folding through the reproduction of Anfinsen’s experiment by undergraduate physical biochemistry students
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER RUIZ SANZ
|
2018 | Articulo |
Protein folding cooperativity and thermodynamic barriers of the simplest beta-sheet fold: a survey of WW domains
JOSE CRISTOBAL MARTINEZ HERRERIAS, RAQUEL GODOY RUIZ
|
2018 | Articulo |
Structural basis for polyamine binding at the dCACHE domain of the McpU chemoreceptor from Pseudomonas putida
BERTRAND MOREL
|
2018 | Articulo |
An auxin controls bacterial antibiotics production
ABDELALI DADDAOUA, BERTRAND MOREL
|
2018 | Articulo |
Diseño biocomputacional de un inhibidor del VIH mimético de la proteína gp41.
BERTRAND MOREL
|
2018 | Trabajo conducente a obtención de DEA |
Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility
BERTRAND MOREL
|
2018 | Articulo |
Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility
BERTRAND MOREL
|
2018 | Articulo |
Natural (and Unnatural) Small Molecules as Pharmacological Chaperones and Inhibitors in Cancer
ANGEL LUIS PEY RODRÍGUEZ
|
2018 | Book-Review |
Potential Pharmacological Chaperones for Cystathionine Beta-Synthase-Deficient Homocystinuria
ANGEL LUIS PEY RODRÍGUEZ
|
2018 | Book-Review |
The role of protein dynamics in loss-of-function disease mechanisms: a NQO1 cancer-associated polymorphism as model
ANGEL LUIS PEY RODRÍGUEZ
|
2018 | Tesis Doctoral |
Improving the Activity and Stability of Human Galactokinase for Therapeutic and Biotechnological Applications.
ANGEL LUIS PEY RODRÍGUEZ
|
2018 | Articulo |
Evolutionary Divergent Suppressor Mutations in Conformational Diseases.
ANGEL LUIS PEY RODRÍGUEZ
|
2018 | Book-Review |
Biophysical and functional perturbation analyses at cancer-associated P187 and K240 sites of the multifunctional NADP(H):quinone oxidoreductase 1.
ANGEL LUIS PEY RODRÍGUEZ
|
2018 | Articulo |
Second Generation of Mannich Base-Type Derivatives with in Vivo Activity against Trypanosoma cruzi
CLOTILDE MARIN SANCHEZ, ANGEL LUIS PEY RODRÍGUEZ, Rubén Martín Escolano
|
2018 | Articulo |
Two acute myeloid leukemia patient subsets are identified based on the constitutive PI3K-Akt-mTOR signaling of their leukemic cells; a functional, proteomic, and transcriptomic comparison
Maria del Carmen Hernandez Valladares
|
2018 | Articulo |
Proteomic Profiling of Primary Human Acute Myeloid Leukemia Cells Does Not Reflect Their Constitutive Release of Soluble Mediators. Proteomes
Maria del Carmen Hernandez Valladares
|
2018 | Articulo |
Insulin-Like Growth Factor-I as an Effector Element of the Cytokine IL-4 in the Development of a Leishmania major Infection
Maria del Carmen Hernandez Valladares
|
2018 | Articulo |
Vacuolar ATPase as a possible therapeutic target in human acute myeloid leukemia
Maria del Carmen Hernandez Valladares
|
2018 | Review |
Preservation Method and Phosphate Buffered Saline Washing Affect the Acute Myeloid Leukemia Proteome
Maria del Carmen Hernandez Valladares
|
2018 | Articulo |
Sublingual Priming with a HIV gp41-Based Subunit Vaccine Elicits Mucosal Antibodies and Persistent B Memory Responses in Non-Human Primates.
FRANCISCO CONEJERO LARA
|
2017 | Articulo |
Sublingual Priming with a HIV gp41-Based Subunit Vaccine Elicits Mucosal Antibodies and Persistent B Memory Responses in Non-Human Primates.
FRANCISCO CONEJERO LARA
|
2017 | Articulo |
The influence of N-terminal acetylation on micelle-induced conformational changes and aggregation of ¿-Synuclein
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2017 | Articulo |
Understanding the contribution of disulfide bridges to the folding and misfolding of an anti-Abeta scFv
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2017 | Articulo |
Towards the improvement in stability of an anti-Abeta single-chain variable fragment, scFv-h3D6, as a way to enhance its therapeutic potential
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER MURCIANO CALLES
|
2017 | Articulo |
Two-Step Amyloid Aggregation: Sequential Lag Phase Intermediates
SALVADOR CASARES ATIENZA, MIGUEL MARTÍN HERNÁNDEZ, ANGEL ORTE GUTIERREZ, MARIA JOSE RUEDAS RAMA, MARÍA DEL MAR ROLDÁN ORTIZ
|
2017 | Articulo |
Magnetite nanoparticles biomineralization in the presence of the magnetosome membrane protein MamC: Effect of protein aggregation and protein structure on magnetite formation
SALVADOR CASARES ATIENZA, CONCEPCION JIMENEZ LOPEZ, ALEJANDRO RODRIGUEZ NAVARRO, ANA ISABEL AZUAGA FORTES, MARÍA ANTONIA FERNÁNDEZ VIVAS
|
2017 | Articulo |
Purification and characterization of Pseudomonas aeruginosa LasR expressed in acyl-homoserine lactone free Escherichia coli cultures
ABDELALI DADDAOUA, BERTRAND MOREL
|
2017 | Articulo |
A mechanism for cancer-associated inactivation of NQO1 due to P187S and its reactivation by the consensus mutation H80R
BERTRAND MOREL, ANGEL LUIS PEY RODRÍGUEZ
|
2017 | Articulo |
Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues
JAVIER MURCIANO CALLES
|
2017 | Articulo |
Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of Polycomb RING1B
ANGEL LUIS PEY RODRÍGUEZ
|
2017 | Articulo |
Enhanced vulnerability of human proteins towards disease-associated inactivation through divergent evolution
MIGUEL BURGOS POYATOS, ANGEL LUIS PEY RODRÍGUEZ, ROGELIO JESÚS PALOMINO MORALES
|
2017 | Articulo |
Thermodynamics of cooperative binding of FAD to human NQO1: Implications to understanding cofactor-dependent function and stability of the flavoproteome
ANGEL LUIS PEY RODRÍGUEZ
|
2017 | Articulo |
Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism.
ANGEL LUIS PEY RODRÍGUEZ
|
2017 | Articulo |
Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
ANGEL LUIS PEY RODRÍGUEZ
|
2017 | Articulo |
Proteogenomics approaches for studying cancer biology and their potential in the identification of acute myeloid leukemia biomarkers
Maria del Carmen Hernandez Valladares
|
2017 | Review |
Rethinking the role of osteoponin in human acute myeloid leukemia
Maria del Carmen Hernandez Valladares
|
2017 | Review |
Therapeutic targeting of leukemic stem cells in acute myeloid leukemia, the biological background for possible strategies
Maria del Carmen Hernandez Valladares
|
2017 | Review |
cGMP Generators, Effectors and Therapeutic Implications
Maria del Carmen Hernandez Valladares
|
2017 | Meeting-Abstract |
Molecular and Physicochemical Factors Governing Solubility of the HIV gp41 Ectodomain
FRANCISCO CONEJERO LARA, SALVADOR CASARES ATIENZA, BERTRAND MOREL
|
2016 | Articulo |
Common features in the folding and misfolding of PDZ domains and beyond: the modulatory effect of domain swapping and extra-elements
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER MURCIANO CALLES
|
2016 | Articulo |
Búsqueda de inhibidores de la interacción entre los dominios L víricos y sus dianas celulares de interés como antivirales de amplio espectro
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2016 | Tesis Doctoral |
Búsqueda de Inhibidores de la Interacción entre los dominios L víricos y sus dianas celulares de interés como antivirales de Amplio espectro
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2016 | Tesis Doctoral |
From Binding-Induced Dynamic Effects in SH3 Structures to Evolutionary Conserved Sectors
JAVIER RUIZ SANZ
|
2016 | Articulo |
CAMBIOS ESTRUCTURALES EN AGREGADOS PRE-AMILOIDOGÉNICOS DEL DOMINIO SH3 DE ¿-ESPECTRINA (STRUCTURAL CHANGES IN PRE-AMYLOIDOGENIC AGGREGATES OF THE SH3 DOMAIN OF ¿-SPECTRIN)
SALVADOR CASARES ATIENZA, ANGEL ORTE GUTIERREZ, MARIA JOSE RUEDAS RAMA
|
2016 | Tesis Doctoral |
Biosynthesis of the acetyl-CoA carboxylase-inhibiting antibiotic, andrimid, in Serratia is regulated by Hfq and the LysR-type transcriptional regulator, AdmX
BERTRAND MOREL
|
2016 | Articulo |
Assessment of the contribution of chemoreceptor-based signalling to biofilm formation
BERTRAND MOREL
|
2016 | Articulo |
Identification of ligands for bacterial sensor proteins
BERTRAND MOREL
|
2016 | Review |
The paralogous ArsR1 and ArsR2 regulators of Pseudomonas putida KT2440 as basis for arsenic biosensor development
BERTRAND MOREL
|
2016 | Articulo |
Identification of a chemoreceptor that specifically mediates chemotaxis towards metabolizable purine derivatives
BERTRAND MOREL
|
2016 | Articulo |
Two different mechanisms mediate chemotaxis to inorganic phosphate in Pseudomonas aeruginosa
BERTRAND MOREL
|
2016 | Articulo |
Caracterizacio¿n de la oligomerizacio¿n de pe¿ptidos de ß-amiloide por espectroscopi¿a de Infrarrojo de Transformada de Fourier
BERTRAND MOREL
|
2016 | Trabajo conducente a obtención de DEA |
A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation
JAVIER MURCIANO CALLES
|
2016 | Articulo |
Tryptophan synthase uses an atypical mechanism to achieve substrate specificity
JAVIER MURCIANO CALLES
|
2016 | Articulo |
Directed evolution of an allosteric tryptophan synthase enzyme to create a platform for synthesis of non-canonical amino acids
JAVIER MURCIANO CALLES
|
2016 | Capítulo de libro |
Expanding the Substrate Scope of TrpB for the Synthesis of Nitrotryptophan
JAVIER MURCIANO CALLES
|
2016 | Trabajo conducente a obtención de DEA |
Búsqueda de inhibidores en la interacción entre los dominios L víricos y sus dianas celulares de interés como antivirales de amplio espectro
JAVIER MURCIANO CALLES
|
2016 | Tesis Doctoral |
Calorimetric approaches to studying complex protein structure-function stability relationships in conformational diseases: the case of cystathionine ß-synthase.
ANGEL LUIS PEY RODRÍGUEZ
|
2016 | Capítulo de libro |
Caenorhabditis elegans alanine:glyoxylate aminotransferase is a mitochondrial and cold-adapted ortholog of peroxisomal human AGT1 key to understand between-species divergence in glyoxylate metabolism
ANGEL LUIS PEY RODRÍGUEZ
|
2016 | Articulo |
Kinetic stability of cystathionine beta-synthase can be modulated by structural analogs of S-adenosylmethionine: Potential approach to pharmacological chaperone therapy for homocystinuria.
ANGEL LUIS PEY RODRÍGUEZ
|
2016 | Articulo |
Molecular basis of classic galactosemia from the structure of human galactose 1-phosphate uridylyltransferase
ANGEL LUIS PEY RODRÍGUEZ
|
2016 | Articulo |
Natural Small Molecules as Stabilizers and Activators of Cancer-Associated NQO1 Polymorphisms.
ANGEL LUIS PEY RODRÍGUEZ
|
2016 | Review |
Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands.
ANGEL LUIS PEY RODRÍGUEZ, ROGELIO JESÚS PALOMINO MORALES
|
2016 | Articulo |
Galactokinase promiscuity: a question of flexibility?
ANGEL LUIS PEY RODRÍGUEZ
|
2016 | Review |
Targeting Cystathionine Beta-Synthase Misfolding in Homocystinuria by Small Ligands: State of the Art and Future Directions.
ANGEL LUIS PEY RODRÍGUEZ
|
2016 | Review |
Experimental and computational evidence on conformational fluctuations as a source of catalytic defects in genetic diseases
ANGEL LUIS PEY RODRÍGUEZ
|
2016 | Articulo |
The chondroitin sulfate/dermatan sulfate 4-O-endosulfatase from marine bacterium Vibrio sp FC509 is a dimeric species: Biophysical characterization of an endosulfatase.
ANGEL LUIS PEY RODRÍGUEZ
|
2016 | Articulo |
Freezing effects on the acute myeloide leukemia cell proteome and phosphoproteome revealed using optimal quantitative workflows
Maria del Carmen Hernandez Valladares
|
2016 | Articulo |
Selecting sample preparation workflows for mass spectrometry-based proteomic and phosphoproteomic analysis of patient samples with acute myeloid leukemia
Maria del Carmen Hernandez Valladares
|
2016 | Review |
How should quality of life assessment be used to evaluate elderly and unfit patients with acute myeloid leukemia?
Maria del Carmen Hernandez Valladares
|
2016 | Review |
Global cell proteome profiling, phospho-signaling and quantitative proteomics for identification of new biomarkers in acute myeloid leukemia patients
Maria del Carmen Hernandez Valladares
|
2016 | Review |
Reliable FASP-based procedures for optimal quantitative proteomic and phosphoproteomic analysis on samples from acute myeloid leukemia patients
Maria del Carmen Hernandez Valladares
|
2016 | Articulo |
SH3 Domains as Suitable Models to Study Amyloid Aggregation
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2015 | Capítulo de libro |
The First Step of Amyloidogenic Aggregation
SALVADOR CASARES ATIENZA, ANGEL ORTE GUTIERREZ, MARIA JOSE RUEDAS RAMA
|
2015 | Articulo |
Molecular binding mechanism of TtgR repressor to antibiotics and antimicrobials
SALVADOR CASARES ATIENZA, BERTRAND MOREL
|
2015 | Articulo |
VERSATILITY OF SH3 DOMAINS IN THE CELLULAR MACHINERY
SALVADOR CASARES ATIENZA, ANA ISABEL AZUAGA FORTES
|
2015 | Capítulo de libro |
Identification of a Chemoreceptor for C2 and C3 Carboxylic Acids.
BERTRAND MOREL
|
2015 | Articulo |
Directed evolution of the tryptophan synthase ß-subunit for stand-alone function recapitulates allosteric activation
JAVIER MURCIANO CALLES
|
2015 | Articulo |
Molecular Recognition of PTS-1 cargo proteins by Pex5p: implications for protein mistargeting in primary hyperoxaluria
ANGEL LUIS PEY RODRÍGUEZ
|
2015 | Articulo |
Comparative proteomic analysis of compartmentalised Ras signalling
Maria del Carmen Hernandez Valladares
|
2015 | Articulo |
Mapping the structure of amyloid nucleation precursors by protein engineering kinetic analysis
FRANCISCO CONEJERO LARA, ANA ISABEL AZUAGA FORTES, BERTRAND MOREL
|
2014 | Articulo |
MULTIDISCIPLINARY ANALYSIS OF THE ENERGETICS AND MECHANISM OF ASSEMBLY OF AMYLOID OLIGOMERIC PRECURSORS
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2014 | Tesis Doctoral |
Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41 with potential as anti-HIV-1 drugs
FRANCISCO CONEJERO LARA, SALVADOR CASARES ATIENZA, BERTRAND MOREL
|
2014 | Articulo |
Thermodynamic Analysis of the Binding of 2F5 (Fab and Immunoglobulin G Forms) to Its gp41 Epitope Reveals a Strong Influence of the Immunoglobulin Fc Region on Affinity
FRANCISCO CONEJERO LARA, SALVADOR CASARES ATIENZA
|
2014 | Articulo |
A thermodynamic study of the third PDZ domain of MAGUK neuronal protein PSD-95 reveals a complex three-state folding behavior
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER MURCIANO CALLES
|
2014 | Articulo |
Alteration of the C-Terminal Ligand Specificity of the Erbin PDZ Domain by Allosteric Mutational Effects
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER MURCIANO CALLES
|
2014 | Articulo |
Post translational modifications modulate ligand recognition by the third PDZ domain of MAGUK protein PSD¿95
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER MURCIANO CALLES
|
2014 | Articulo |
The impact of extra-domain structures and post-translational modifications in the folding/misfolding behaviour of the third PDZ domain of MAGUK neuronal protein PSD-95
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER MURCIANO CALLES
|
2014 | Articulo |
Interacciones cooperativas y efectos contextuales en dominios SH3 y WW
JAVIER RUIZ SANZ
|
2014 | Tesis Doctoral |
Identification of new residues involved in intramolecular signal transmission in a prokaryotic transcriptional repressor
BERTRAND MOREL
|
2014 | Articulo |
pH-dependent relationship between thermodynamic and kinetic stability in the denaturation of human phosphoglycerate kinase 1
ANGEL LUIS PEY RODRÍGUEZ
|
2014 | Articulo |
The role of surface electrostatics on the stability, function and regulation of human cystathionine ß-synthase, a complex multidomain and oligomeric protein
ANGEL LUIS PEY RODRÍGUEZ
|
2014 | Articulo |
Domain Organization, Catalysis and Regulation of Eukaryotic Cystathionine Beta-Synthases
ANGEL LUIS PEY RODRÍGUEZ
|
2014 | Articulo |
FAD binding overcomes defects in activity and stability displayed by cancer-associated variants of human NQO1
ANGEL LUIS PEY RODRÍGUEZ
|
2014 | Articulo |
The lower limits for protein stability and foldability in primary hyperoxaluria type I
ANGEL LUIS PEY RODRÍGUEZ
|
2014 | Articulo |
The consensus-based approach for gene/enzyme replacement therapies and crystallization strategies: the case of human alanine¿glyoxylate aminotransferase
JOSE MANUEL SANCHEZ RUIZ, ANGEL LUIS PEY RODRÍGUEZ
|
2014 | Articulo |
Insights into human phosphoglycerate kinase 1 deficiency as a conformational disease from biochemical, biophysical, and in vitro expression analyses
ANGEL LUIS PEY RODRÍGUEZ
|
2014 | Articulo |
The metastability of human UDP-galactose 4¿-epimerase (GALE) is increased by variants associated with type III galactosemia but decreased by substrate and cofactor binding
ANGEL LUIS PEY RODRÍGUEZ
|
2014 | Articulo |
MOLECULAR MECHANISMS UNDERLYING PRIMARY HYPEROXALURIA TYPE I AND NEW THERAPEUTIC APPROACHES
ANGEL LUIS PEY RODRÍGUEZ
|
2014 | Tesis Doctoral |
Dinámica conformacional de la enzima NQO1: efecto de polimorfismos asociados a cáncer y de la unión de FAD
ANGEL LUIS PEY RODRÍGUEZ
|
2014 | Trabajo conducente a obtención de DEA |
Identification of polyketide inhibitors targeting 3-dehydroquinate dehydratase in the shikimate pathway of Enterococcus faecalis
Maria del Carmen Hernandez Valladares
|
2014 | Articulo |
Host susceptibility to malaria in human and mice: compatible approaches to identify potential resistant genes
Maria del Carmen Hernandez Valladares
|
2014 | Review |
Quantitative proteomic analysis of compartmentalized signaling networks
Maria del Carmen Hernandez Valladares
|
2014 | Articulo |
Modulation of the stability of amyloidogenic precursors by anion binding strongly influences the rate of amyloid nucleation
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2013 | Articulo |
Biophysical characterization of HIV-1 vaccine candidates derived from gp41
FRANCISCO CONEJERO LARA, SALVADOR CASARES ATIENZA
|
2013 | Tesis Doctoral |
Isothermal titration calorimetry: thermodynamic analysis of the binding thermograms of molecular recognition events by using equilibrium models
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER RUIZ SANZ, JAVIER MURCIANO CALLES
|
2013 | Capítulo de libro |
Two-state dynamics of the SH3-SH2 tandem of Abl kinase and the allosteric role of the N-cap.
JAVIER RUIZ SANZ
|
2013 | Articulo |
Distinct ubiquitin binding modes exhibited by SH3 domains: Molecular determinants and functional implications
SALVADOR CASARES ATIENZA, ANA ISABEL AZUAGA FORTES
|
2013 | Articulo |
Multimeric and differential binding of CIN85/CD2AP with two atypical proline-rich sequences from CD2 and Cbl-b
SALVADOR CASARES ATIENZA, ANA ISABEL AZUAGA FORTES
|
2013 | Articulo |
Paralogous chemoreceptors mediate chemotaxis towards protein amino acids and the non-protein amino acid gamma-aminobutyrate (GABA)
BERTRAND MOREL, CRISTINA GARCIA FONTANA
|
2013 | Articulo |
High Specificity in CheR Methyltransferase Function: CheR2 of pseudomonas putida is essential for chemotaxis, whereas CheR1 is involved in biofilm formation
BERTRAND MOREL, CRISTINA GARCIA FONTANA
|
2013 | Articulo |
Optimización del proceso de purificación de una nueva miniproteína basada en el polipéptido pancreático aviar
JAVIER MURCIANO CALLES
|
2013 | Trabajo conducente a obtención de DEA |
Trabajo fin de grado Magdalena Baran
JAVIER MURCIANO CALLES
|
2013 | Proyecto fin de carrera |
Structural and energetic basis of protein kinetic destabilization in human phosphoglycerate kinase 1 deficiency.
ANGEL LUIS PEY RODRÍGUEZ
|
2013 | Articulo |
Protein homeostasis defects of alanine-glyoxylate aminotransferase: new therapeutic strategies in primary hyperoxaluria type I.
ANGEL LUIS PEY RODRÍGUEZ
|
2013 | Review |
The role of protein denaturation energetics and molecular chaperones in the aggregation and mistargeting of mutants causing primary hyperoxaluria type I
ANGEL LUIS PEY RODRÍGUEZ
|
2013 | Articulo |
Protein homeostasis disorders of key enzymes of amino acids metabolism: mutation-induced protein kinetic destabilization and new therapeutic strategies.
ANGEL LUIS PEY RODRÍGUEZ
|
2013 | Review |
The interplay between protein stability and dynamics in conformational diseases: The case of hPGK1 deficiency.
ANGEL LUIS PEY RODRÍGUEZ
|
2013 | Articulo |
The role of palmitoylation in regulating Ras localization and function
Maria del Carmen Hernandez Valladares
|
2013 | Review |
Characterization of Oligomers of Heterogeneous Size as Precursors of Amyloid Fibril Nucleation of an SH3 Domain: An Experimental Kinetics Study
FRANCISCO CONEJERO LARA, ANA ISABEL AZUAGA FORTES, BERTRAND MOREL
|
2012 | Articulo |
Thermodynamic impact of embedded water molecules in the unfolding of human CD2BP2-GYF domain
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2012 | Articulo |
Aspectos dinámicos de reconocimiento de ligandos y regulación funcional de dominios SH3: hidratación, cooperatividad y equilibrio conformacional
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2012 | Tesis Doctoral |
The Interconversion between a Flexible ß-Sheet and a Fibril ß-Arrangement Constitutes the Main Conformational Event during Misfolding of PSD95-PDZ3 Domain
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER MURCIANO CALLES
|
2012 | Articulo |
Interfacial water molecules in SH3 interactions: A revised paradigm for polyproline recognition
JAVIER RUIZ SANZ
|
2012 | Articulo |
The promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A protein
JAVIER RUIZ SANZ
|
2012 | Articulo |
Bulk and Single-Molecule Fluorescence Studies of the Saturation of the DNA Double Helix Using YOYO¿3 Intercalator Dye
SALVADOR CASARES ATIENZA, ANGEL ORTE GUTIERREZ, MARIA JOSE RUEDAS RAMA
|
2012 | Articulo |
Early Amyloidogenic Oligomerization Studied through Fluorescence Lifetime Correlation Spectroscopy
SALVADOR CASARES ATIENZA, ANGEL ORTE GUTIERREZ, MARIA JOSE RUEDAS RAMA, ELENA FERNANDEZ FERNANDEZ
|
2012 | Articulo |
A designed point mutant in fis1 disrupts dimerization and mitochondrial fission
SALVADOR CASARES ATIENZA
|
2012 | Articulo |
Primary hyperoxalurias: Disorders of glyoxylate detoxification
ANGEL LUIS PEY RODRÍGUEZ
|
2012 | Review |
Conformational Properties of Nine Purified Cystathionine ß-Synthase Mutants
ANGEL LUIS PEY RODRÍGUEZ
|
2012 | Articulo |
UNDERSTANDING THE POLYMORPHIC BEHAVIOUR OF A MUTANT OF THE ALPHA-SPECTRIN SH3 DOMAIN BY MEANS OF TWO 1.1 A RESOLUTION STRUCTURES
FRANCISCO CONEJERO LARA, JOSE CRISTOBAL MARTINEZ HERRERIAS, SALVADOR CASARES ATIENZA
|
2011 | Articulo |
A COMPARATIVE ANALYSIS OF THE FOLDING AND MISFOLDING PATHWAYS OF THE THIRD PDZ DOMAIN OF PSD95 INVESTIGATED UNDER DIFFERENT PH CONDITIONS
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER MURCIANO CALLES
|
2011 | Articulo |
Caracterización termodinámico-estructural de la estabilidad de dominios PDZ y análisis de su especificidad de unión mediante librerías de expresión en fagos
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER MURCIANO CALLES
|
2011 | Tesis Doctoral |
Efectos alostéricos a larga distancia en dominios SH3. Estudio de las interacciones del dominio c-Src-SH3 con el ligando rico en prolina RLP
JAVIER RUIZ SANZ
|
2011 | Trabajo conducente a obtención de DEA |
Three-state thermal unfolding of onconase
SALVADOR CASARES ATIENZA
|
2011 | Articulo |
MARCAJE ISOTÓPICO DIFERENCIAL DE LOS DOMINIOS SH3 DE CD2AP EN TANDEM
ANA ISABEL AZUAGA FORTES
|
2011 | Trabajo conducente a obtención de DEA |
Solution structure, dynamics and thermodynamics of the three SH3 domains of CD2AP
ANA ISABEL AZUAGA FORTES
|
2011 | Articulo |
Intramolecular signal transmission in a tetrameric repressor of the IclR family.
BERTRAND MOREL
|
2011 | Articulo |
The Regulatory Subunit of PKA-I Remains Partially Structured and Undergoes ¿-Aggregation upon Thermal Denaturation
ANGEL LUIS PEY RODRÍGUEZ
|
2011 | Articulo |
DIVERGENCE IN ENZYME REGULATION BETWEEN C. ELEGANS AND HUMAN TYROSINE HYDROXYLASE, THE KEY ENZYME IN THE SYNTHESIS OF DOPAMINE¿.
ANGEL LUIS PEY RODRÍGUEZ
|
2011 | Articulo |
Role of low native state kinetic stability and interaction of partially unfolded states with molecular chaperones in the mitocondrial protein mistargeting associated with primary hyperoxaluria
JOSE MANUEL SANCHEZ RUIZ, ANGEL LUIS PEY RODRÍGUEZ
|
2011 | Articulo |
Actin polymerazation Dynamics-Insights from In vitro TIRF microscopy
Maria del Carmen Hernandez Valladares
|
2011 | Meeting-Abstract |
KINETIC, STRUCTURAL AND THERMODYNAMIC DETERMINANTS OF AMYLOID FIBRIL FORMATION BY THE ALPHA SPECTRIN SH3 DOMAIN
FRANCISCO CONEJERO LARA, ANA ISABEL AZUAGA FORTES
|
2010 | Tesis Doctoral |
IDENTIFICATION OF A CHEMORECEPTOR FOR TCA CYCLE INTERMEDIATES: DIFFERENTIAL CHEMOTACTIC RESPONSE TOWARDS RECEPTOR LIGANDS.
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2010 | Articulo |
ENVIRONMENTAL CONDITIONS AFFECT THE KINETICS OF NUCLEATION OF AMYLOID FIBRILS AND DETERMINE THEIR MORPHOLOGY
FRANCISCO CONEJERO LARA, ANA ISABEL AZUAGA FORTES, BERTRAND MOREL
|
2010 | Articulo |
THE THERMODYNAMIC STABILITY OF AMYLOID FIBRILS STUDIED BY DIFFERENTIAL SCANNING CALORIMETRY
FRANCISCO CONEJERO LARA, BERTRAND MOREL
|
2010 | Articulo |
NOVEL CONFORMATIONAL ASPECTS OF THE THIRD PDZ DOMAIN OF THE NEURONAL POST-SYNAPTIC DENSITY-95 PROTEIN REVEALED FROM TWO 1.4A X-RAY STRUCTURES.
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER MURCIANO CALLES
|
2010 | Articulo |
ROLE OF INTERFACIAL WATER MOLECULES IN PROLINE-RICH LIGAND RECOGNITION BY THE SRC HOMOLOGY 3 DOMAIN OF ABL
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2010 | Articulo |
AN OLIGOMERIC EQUILIBRIUM INTERMEDIATE AS THE PRECURSORY NUCLEUS OF GLOBULAR AND FIBRILLAR SUPRA-MACROMOLECULAR ASSEMBLIES IN A PDZ DOMAIN
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER MURCIANO CALLES
|
2010 | Articulo |
DIFFERENTIAL SCANNING CALORIMETRY: THERMODYNAMIC ANALYSIS OF THE UNFOLDING TRANSITIONS OF PROTEINS, DOMAINS AND PEPTIDIC FRAGMENTS BY USING EQUILIBRIUM MODELS
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER RUIZ SANZ
|
2010 | Capítulo de libro |
DETERMINANTES MOLECULARES DE LA AFINIDAD Y ESPECIFICIDAD DE UNIÓN EN DOMINIOS SH3
JAVIER RUIZ SANZ
|
2010 | Tesis Doctoral |
STRUCTURE AND THERMODYNAMICS OF THE CD2AP-SH3 DOMAINS AND THEIR INTERACTION WITH UBIQUITIN
ANA ISABEL AZUAGA FORTES
|
2010 | Tesis Doctoral |
COMPARTMENTALISED GLUCOSE METABOLISM IN PSEUDOMONAS PUTIDA IS CONTROLLED BY THE PTXS REPRESSOR.
ABDELALI DADDAOUA, BERTRAND MOREL
|
2010 | Articulo |
THE STRUCTURAL AND ENERGETIC BASIS FOR HIGH SELECTIVITY IN A HIGH-AFFINITY PROTEIN-PROTEIN INTERACTION
BERTRAND MOREL
|
2010 | Articulo |
MODULATION OF BURIED IONIZABLE GROUPS IN PROTEINS WITH ENGINEERED SURFACE CHARGE
JOSE MANUEL SANCHEZ RUIZ, ANGEL LUIS PEY RODRÍGUEZ
|
2010 | Articulo |
PHENYLALANINE HYDROXYLASE EXPRESSION IN PRIMARY RAT HEPATOCYTES IS MODULATED BY OXYGEN CONCENTRATION
ANGEL LUIS PEY RODRÍGUEZ
|
2010 | Articulo |
SUPERSTOICHIOMETRIC BINDING OF L-PHE TO PHENYLALANINE HYDROXYLASE FROM CAENORHABDITIS ELEGANS: EVOLUTIONARY IMPLICATIONS
ANGEL LUIS PEY RODRÍGUEZ
|
2010 | Articulo |
EFFECT OF PHARMACOLOGICAL CHAPERONES ON BRAIN TYROSINE HYDROXYLASE AND TRYPTOPHAN HYDROXYLASE 2.
ANGEL LUIS PEY RODRÍGUEZ
|
2010 | Articulo |
Structural characterization of a capping protein interaction motif defines a family of actin filament regulators
Maria del Carmen Hernandez Valladares
|
2010 | Articulo |
EVALUATION OF FOLDING CO-OPERATIVITY OF A CHIMERIC PROTEIN BASED ON THE MOLECULAR RECOGNITION BETWEEN POLYPROLINE LIGANDS AND SH3 DOMAINS
FRANCISCO CONEJERO LARA, JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2009 | Articulo |
A SINGLE MUTATION IN AN SH3 DOMAIN INCREASES AMYLOID AGGREGATION BY ACCELERATING NUCLEATION, BUT NOT BY DESTABILIZING THERMODYNAMICALLY THE NATIVE STATE
FRANCISCO CONEJERO LARA, ANA ISABEL AZUAGA FORTES, BERTRAND MOREL
|
2009 | Articulo |
THERMODYNAMIC CHARACTERIZATION OF THE FOLDING EQUILIBRIUM OF THE HUMAN NEDD4-WW4 DOMAIN: AT THE FRONTIERS OF COOPERATIVE FOLDING
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER RUIZ SANZ
|
2009 | Articulo |
INTERTWINED DIMERIC STRUCTURE FOR THE SH3 DOMAIN OF THE C-SRC TYROSINE KINASE INDUCED BY POLYETHYLENE GLYCOL BINDING
JAVIER RUIZ SANZ, BERTRAND MOREL
|
2009 | Articulo |
THE EFFECT OF A PROLINE RESIDUE ON THE RATE OF GROWTH AND THE SPACE GROUP OF ALPHA-SPECTRIN SH3-DOMAIN CRYSTALS
SALVADOR CASARES ATIENZA
|
2009 | Articulo |
EVIDENCE FOR CONFORMATIONAL HETEROGENEITY OF FISSION PROTEIN FIS1 FROM SACCHAROMYCES CEREVISIAE
SALVADOR CASARES ATIENZA
|
2009 | Articulo |
ACCURATE CHARACTERIZATION OF WEAK MACROMOLECULAR INTERACTIONS BY TITRATION OF NMR RESIDUAL DIPOLAR COUPLINGS: APPLICATION TO THE CD2AP SH3-C:UBIQUITIN COMPLEX
ANA ISABEL AZUAGA FORTES
|
2009 | Articulo |
BIOCHEMICAL CHARACTERIZATION OF MUTANT PHENYLALANINE HYDROXYLASE ENZYMES AND CORRELATION WITH CLINICAL PRESENTATION IN HYPERPHENYLALANINAEMIC PATIENTS
ANGEL LUIS PEY RODRÍGUEZ
|
2009 | Articulo |
IRON BINDING EFFECTS ON THE KINETIC STABILITY AND UNFOLDING ENERGETICS OF A THERMOPHILIC PHENYLALANINE HYDROXYLASE FROM CHLOROFLEXUS AURANTIACUS
ANGEL LUIS PEY RODRÍGUEZ
|
2009 | Articulo |
Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin
Maria del Carmen Hernandez Valladares
|
2009 | Articulo |
DISEÑO Y CARACTERIZACION DE PROTEINAS QUIMERICAS PARA EL ESTUDIO DEL RECONOCIMIENTO MOLECULAR ENTRE LIGANDOS PEPTIDICOS Y DOMINIOS SH3
FRANCISCO CONEJERO LARA, JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2008 | Tesis Doctoral |
ANALYSIS OF THE THERMODYNAMICS OF BINDING OF AN SH3 DOMAIN TO PROLINE-RICH PEPTIDES USING A CHIMERIC FUSION PROTEIN
FRANCISCO CONEJERO LARA, JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2008 | Articulo |
RECONOCIMIENTO DE SECUENCIAS RICAS EN PROLINA POR DOMINIOS MODULARES DE INTERACCIÓN PROTEÍNA-PROTEÍNA
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2008 | Tesis Doctoral |
AN ERROR ANALYSIS FOR TWO-STATE PROTEIN-FOLDING KINETIC PARAMETERS AND PHI-VALUES: PROGRESS TOWARD PRECISION BY EXPLORING PH DEPENDENCIES ON LEFFLER PLOTS
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2008 | Articulo |
DISEÑO Y CARACTERIZACION DE PROTEINAS QUIMERICAS PARA EL ESTUDIO DEL RECONOCIMIENTO MOLECULAR ENTRE LIGANDOS PEPTIDICOS Y DOMINIOS SH3
SALVADOR CASARES ATIENZA
|
2008 | Tesis Doctoral |
A MODEL FOR THE AGGREGATION OF THE ACYLPHOSPHATASE FROM SULFOLOBUS SOLFATARICUS IN ITS NATIVE-LIKE STATE
ANA ISABEL AZUAGA FORTES
|
2008 | Articulo |
ENGINEERING PROTEINS WITH TUNABLE THERMODYNAMIC AND KINETIC STABILITIES
JOSE MANUEL SANCHEZ RUIZ, ANGEL LUIS PEY RODRÍGUEZ, RAQUEL GODOY RUIZ
|
2008 | Articulo |
IDENTIFICATION OF PHARMACOLOGICAL CHAPERONES AS POTENTIAL THERAPEUTIC AGENTS TO TREAT PHENYLKETONURIA
ANGEL LUIS PEY RODRÍGUEZ
|
2008 | Articulo |
THERMOPLASMA ACIDOPHILUM CDC6 PROTEIN STIMULATES MCM HELICASE ACTIVITY BY REGULATION ITS ATPASE ACTIVITY
ANGEL LUIS PEY RODRÍGUEZ
|
2008 | Articulo |
ANABOLIC FUNCTION OF PHENYLALANINE HYDROXYLASE IN CAENORHABDITIS ELEGANS
ANGEL LUIS PEY RODRÍGUEZ
|
2008 | Articulo |
COOPERATIVE PROPAGATION OF LOCAL STABILITY CHANGES FROM LOW-STABILITY AND HIGH-STABILITY REGIONS IN A SHV3 DOMAIN
FRANCISCO CONEJERO LARA, SALVADOR CASARES ATIENZA
|
2007 | Articulo |
THE HIGH-RESOLUTION NMR STRUCTURE OF THE R21A SPC-SH3:P41 COMPLEX: UNDERSTANDING THE DETERMINANTS OF BINDING AFFINITY BY COMPARISON WITH ABL-SH3
FRANCISCO CONEJERO LARA, SALVADOR CASARES ATIENZA
|
2007 | Articulo |
THE HIGH-RESOLUTION NMR STRUCTURE OF A SINGLE-CHAIN CHIMERIC PROTEIN MIMICKING A SH3-PEPTIDE COMPLEX.
FRANCISCO CONEJERO LARA, JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2007 | Articulo |
CRYSTALLIZATION BY CAPILLARY COUNTER-DIFFUSION AND STRUCTURE DETERMINATION OF THE N114A MUTANT OF THE SH3 DOMAIN OF ABL TYROSINE KINASE COMPLEXED WITH A HIGH-AFFINITY PEPTIDE LIGAND
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2007 | Articulo |
CRYSTALLOGRAPHIC STRUCTURE OF THE SH3 DOMAIN OF THE HUMAN C-YES TYROSINE KINASE: LOOP FLEXIBILITY AND AMYLOID AGGREGATION
JAVIER RUIZ SANZ
|
2007 | Articulo |
CARACTERIZACIÓN BIOFÍSICA DE LOS DOMINIOS SH3-B Y SH3-C DE CD2AP
ANA ISABEL AZUAGA FORTES
|
2007 | Trabajo conducente a obtención de DEA |
DETERMINACIÓN DE LA ESTRUCTURA TRIDIMENSIONAL MEDIANTE RMN Y CARACTERIZACIÓN TERMODINÁMICA DEL DOMINIOS SH3-C DE CD2AP
ANA ISABEL AZUAGA FORTES
|
2007 | Trabajo conducente a obtención de DEA |
THE HIGH RESOLUTION NMR STRUCTURE OF THE THIRD SH3 DOMAIN OF CD2AP
ANA ISABEL AZUAGA FORTES
|
2007 | Articulo |
STRUCTURE OF PHENYLALANINE HYDROXYLASE FROM COLWELLIA PSYCHRERYTHRAEA 34H, A MONOMERIC COLD ACTIVE ENZYME WITH LOCAL FLEXIBILITY AROUND THE ACTIVE SITE AND HIGH OVERALL STABILITY
ANGEL LUIS PEY RODRÍGUEZ
|
2007 | Articulo |
PREDICTED EFFECTS OF MISSENSE MUTATIONS OF NATIVE-STATE STABILITY ACCOUNT FOR PHENOTYPIC OUTCOME IN PHENYLKETONURIA, A PARADIGM OF MISFOLDING DISEASES
ANGEL LUIS PEY RODRÍGUEZ
|
2007 | Articulo |
TETRAHYDROBIOPTERIN FOR PATIENTS WITH PHENYLKETONURIA
ANGEL LUIS PEY RODRÍGUEZ
|
2007 | Letters |
Gene-knockout mice in malaria research: useful or misleading?
Maria del Carmen Hernandez Valladares
|
2007 | Review |
A SINGLE MUTATION INDUCES AMYLOID AGGREGATION IN THE [ALPHA]-SPECTRIN SH3 DOMAIN: ANALYSIS OF THE EARLY STAGES OF FIBRIL FORMATION
FRANCISCO CONEJERO LARA, SALVADOR CASARES ATIENZA, BERTRAND MOREL
|
2006 | Articulo |
STRUCTURE OF HUMAN TSG101 UEV DOMAIN.
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2006 | Articulo |
KINETIC ANALYSIS AND MODELLING OF THE ALLOSTERIC BEHAVIOUR OF LIVER AND MUSCLE GLYCOGEN PHOSPHORYLASES
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2006 | Articulo |
COMPARATIVE NMR STUDY ON THE IMPACT OF POINT MUTATIONS ON PROTEIN STABILITY OF PSEUDOMONAS MENDOCINA LIPASE
ANA ISABEL AZUAGA FORTES
|
2006 | Articulo |
SPECIFIC INTERACTION OF THE DIASTEREOMERS 7(R)- AND 7(S)-TETRAHYDROBIOPTERIN WITH PHENYLALANINE HYDROXYLASE: IMPLICATIONS FOR UNDERSTANDING PRIMAPTERINURIA AND VITILIGO
ANGEL LUIS PEY RODRÍGUEZ
|
2006 | Articulo |
Pathology of Tnf-deficient mice infected with Plasmodium chabaudi adami 408XZ
Maria del Carmen Hernandez Valladares
|
2006 | Articulo |
Reliable transfection of Plasmodium falciparum using non-commercial plasmid mini preparations
Maria del Carmen Hernandez Valladares
|
2006 | Articulo |
BINDING CURVES BY CONTINUOUS GRADIENT FLOW-MIX CALORIMETRY
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2005 | Articulo |
ROLE OF THE SURFACE CHARGES D72 AND K8 IN THE FUNCTION AND STRUCTURAL STABILITY OF THE CYTOCHROME C(6) FROM NOSTOC SP PCC 7119
JAVIER RUIZ SANZ
|
2005 | Articulo |
PLAN DE ACCIÓN TUTORIAL PARA PRIMER CURSO DE INGENIERO QUÍMICO
ANA MARIA GARCIA CAMPAÑA, JAVIER RUIZ SANZ, María Monsalud del Olmo Iruela, EMILIA MARIA GUADIX ESCOBAR, ANA ISABEL GARCIA LOPEZ, JOSE MARIA VICARIA RIVILLAS, GERMÁN LUZÓN GONZÁLEZ, MERCEDES FERNANDEZ SERRANO
|
2005 | Articulo |
HPR AS A MODEL PROTEIN IN STRUCTURE, INTERACTION, FOLDING AND STABILITY STUDIES
ANA ISABEL AZUAGA FORTES
|
2005 | Review |
THE ACTIVITY OF WILD TYPE AND MUTANT PHENYLALANINE HYDROXYLASE AND ITS REGULATION BY PHENYLALANINE AND TETRAHYDROBIOPTERIN AT PHYSIOLOGICAL AND PATHOLOGICAL CONCENTRATIONS: AND ISOTHERMAL TITRATION CALORIMETRY STUDY
ANGEL LUIS PEY RODRÍGUEZ
|
2005 | Articulo |
Genetic resistance to malaria in mouse models
Maria del Carmen Hernandez Valladares
|
2005 | Review |
TNF as a malaria candidate gene: polymorphism-screening and family-based association analysis of malaria attack and parasitemia in a population living in Burkina Faso
Maria del Carmen Hernandez Valladares
|
2005 | Articulo |
DETECTION AND CHARACTERIZATION OF PARTIALLY UNFOLDED OLIGOMERS OF THE SH3 DOMAIN OF ALPHA-SPECTRIN
FRANCISCO CONEJERO LARA, SALVADOR CASARES ATIENZA
|
2004 | Articulo |
Diseño y caracterización del reconocimiento molecular entre peptídos y dominios SH3
FRANCISCO CONEJERO LARA, JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2004 | Trabajo conducente a obtención de DEA |
A MINIPROTEIN SCAFFOLD USED TO ASSEMBLE THE POLYPROLINE II BINDING EPITOPE RECOGNIZED BY SH3 DOMAINS
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER RUIZ SANZ
|
2004 | Articulo |
THERMODYNAMIC DISSECTION OF THE BINDING ENERGETICS OF PROLINE-RICH PEPTIDES TO THE ABL-SH3 DOMAIN: IMPLICATIONS FOR RATIONAL LIGAND DESIGN
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2004 | Articulo |
THERMODYNAMIC ANALYSIS OF THE UNFOLDING AND STABILITY OF THE DIMERIC DNA-BINDING PROTEIN HU FROM THE HYPERTHERMOPHILIC EUBACTERIUM THERMOTOGA MARITIMA AND ITS E34D MUTANT
JAVIER RUIZ SANZ
|
2004 | Articulo |
Efecto de mutaciones sobre la estructura-función de la proteína fenilalanina hidroxilasa. Mecanismos moleculares responsables de la respuesta a tetrahidrobiopterina en fenilcetonuria¿. Angel L. Pey Rodríguez
ANGEL LUIS PEY RODRÍGUEZ
|
2004 | Tesis Doctoral |
MECHANISMS UNDERLYING RESPONSIVENESS TO TETRAHYDROBIOPTERIN IN MILD PHENYLKETONURIA MUTATIONS
ANGEL LUIS PEY RODRÍGUEZ
|
2004 | Articulo |
CORRECTION OF KINETIC AND STABILITY DEFECTS BY TETRAHYDROBIOPTERIN IN PHENYLKETONURIA PATIENTS WITH CERTAIN PHENYLALANINE HYDROXYLASE MUTATIONS
ANGEL LUIS PEY RODRÍGUEZ
|
2004 | Articulo |
THERMODYNAMIC CHARACTERIZATION OF THE BINDING OF TETRAHYDROPTERINS TO PHENYLALANINE HYDROXYLASE
ANGEL LUIS PEY RODRÍGUEZ
|
2004 | Articulo |
Confirmation and dissection of QTL controlling resistance to malaria in mice
Maria del Carmen Hernandez Valladares
|
2004 | Articulo |
Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi
Maria del Carmen Hernandez Valladares
|
2004 | Articulo |
Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33
Maria del Carmen Hernandez Valladares
|
2004 | Articulo |
ANÁLISIS DE LAS RUTAS COOPERATIVAS DE PROPAGACIÓN DE ESTABILIDAD EN EL DOMINIO SH3. APLICACIÓN AL ESTUDIO DE LAS INTERACCIONES PROTEÍNA-LIGANDO
FRANCISCO CONEJERO LARA, SALVADOR CASARES ATIENZA
|
2003 | Tesis Doctoral |
A BINDING EVENT CONVERTED INTO A FOLDING EVENT
FRANCISCO CONEJERO LARA, JOSE CRISTOBAL MARTINEZ HERRERIAS, SALVADOR CASARES ATIENZA
|
2003 | Articulo |
STRUCTURAL COOPERATIVITY IN THE SH3 DOMAIN STUDIED BY SITE- DIRECTED MUTAGENESIS AND AMIDE HYDROGEN EXCHANGE
FRANCISCO CONEJERO LARA, JOSE CRISTOBAL MARTINEZ HERRERIAS, SALVADOR CASARES ATIENZA
|
2003 | Articulo |
A THERMODYNAMIC AND KINETIC ANALYSIS OF THE FOLDING PATHWAY OF AN SH3 DOMAIN ENTROPICALLY STABILISED BY A REDESIGNED HYDROPHOBIC CORE
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2003 | Articulo |
CHARACTERIZATION OF SINGLE-TRYPTOPHAN MUTANTS OF HISTIDINE- CONTAINING PHOSPHOCARRIER PROTEIN: EVIDENCE FOR LOCAL REARRANGEMENTS DURING FOLDING FROM HIGH CONCENTRATIONS OF DENATURAN
ANA ISABEL AZUAGA FORTES
|
2003 | Articulo |
CARACTERIZACIÓN ESTRUCTURAL Y COMPUTACIONAL DE RECONOCIMIENTO MOLECULAR DE LAS INTERACCIONES ENTRE COLICINAS
BERTRAND MOREL
|
2003 | Tesis Doctoral |
PHENYLKETONURIA: GENOTYPE-PHENOTYPE CORRELATIONS BASED ON EXPRESSION ANALYSIS OF STRUCTURAL AND FUNCTIONAL MUTATIONS IN PAH
ANGEL LUIS PEY RODRÍGUEZ
|
2003 | Articulo |
THE TEMPERATURE DEPENDENCE OF THE HYDROGEN EXCHANGE IN THE SH3 DOMAIN OF [ALPHA]-SPECTRIN
FRANCISCO CONEJERO LARA, SALVADOR CASARES ATIENZA
|
2002 | Articulo |
UNFOLDING AND AGGREGATION DURING THE THERMAL DENATURATION OF STREPTOKINASE
FRANCISCO CONEJERO LARA, ANA ISABEL AZUAGA FORTES
|
2002 | Articulo |
PH DEPENDENCE OF THE HYDROGEN EXCHANGE IN THE SH3 DOMAIN OF [ALPHA]-SPECTRIN
FRANCISCO CONEJERO LARA, JOSE CRISTOBAL MARTINEZ HERRERIAS, SALVADOR CASARES ATIENZA
|
2002 | Articulo |
ESTABILIDAD, PLEGAMIENTO Y ESTRUCTURA DE LA PROTEÍNA CIRCULAR AS-48 Y DE MUTANTES DEL DOMINIO SH3
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2002 | Tesis Doctoral |
THE DENATURATION OF CIRCULAR ENTEROCIN AS-48 BY UREA AND GUANIDINIUM HYDROCHLORIDE
JOSE CRISTOBAL MARTINEZ HERRERIAS, ANTONIO MIGUEL GÁLVEZ DEL POSTIGO RUIZ
|
2002 | Articulo |
THE CYTOTOXIC DOMAIN OF COLICIN E9 IS A CHANNEL-FORMING ENDONUCLEASE
BERTRAND MOREL
|
2002 | Articulo |
AS-48: A CIRCULAR PROTEIN WITH AN EXTREMELY STABLE GLOBULAR STRUCTURE
JOSE CRISTOBAL MARTINEZ HERRERIAS, ANTONIO MIGUEL GÁLVEZ DEL POSTIGO RUIZ
|
2001 | Articulo |
Inactivation of Aeromonas hydrophila metallo-ß-lactamase by cephamycins and moxalactam
Maria del Carmen Hernandez Valladares
|
2001 | Articulo |
ESTUDIO TERMODINAMICO DE LOS ESTADOS PARCIALMENTE PLEGADOS DEL DOMINIO SH3 DE ALFA-ESPECTRINA
FRANCISCO CONEJERO LARA
|
2000 | Tesis Doctoral |
THERMODYNAMIC ANALYSIS OF HELIX-ENGINEERED FORMS OF THE ACTIVATION DOMAIN OF HUMAN PROCARBOXYPEPTIDASE A2
FRANCISCO CONEJERO LARA, JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2000 | Articulo |
THERMODYNAMIC AND STRUCTURAL CHARACTERIZATION OF ASN AND ALA RESIDUES IN THE DISALLOWED II ‘ REGION OF THE RAMACHANDRAN PLOT
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
2000 | Articulo |
THE IONIZATION OF A BURIED GLUTAMIC ACID IS THERMODYNAMICALLY LINKED TO THE STABILITY OF LEISHMANIA MEXICANA TRIOSE PHOSPHATE ISOMERASE
JAVIER RUIZ SANZ
|
2000 | Articulo |
Efecto del estanozolol
ANGEL LUIS PEY RODRÍGUEZ
|
2000 | Tesina |
Kinetic and spectroscopic characterization of the native and metal-substituted ß-lactamase from Aeromonas hydrophila AE036
Maria del Carmen Hernandez Valladares
|
2000 | Articulo |
THE NATIVE STATE CONFORMATIONAL ENSEMBLE OF THE SH3 DOMAIN FROM ALPHA-SPECTRIN
FRANCISCO CONEJERO LARA, SALVADOR CASARES ATIENZA
|
1999 | Articulo |
EXPRESSION AND CHARACTERIZATION OF THE INTACT N-TERMINAL DOMAIN OF STREPTOKINASE
FRANCISCO CONEJERO LARA, ANA ISABEL AZUAGA FORTES
|
1999 | Articulo |
THE FOLDING TRANSITION STATE BETWEEN SH3 DOMAINS IS CONFORMATIONALLY RESTRICTED AND EVOLUTIONARILY CONSERVED
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
1999 | Articulo |
THERMODYNAMIC ANALYSIS OF ALPHA-SPECTRIN SH3 AND TWO OF ITS CIRCULAR PERMUTANTS WITH DIFFERENT LOOP LENGTHS: DISCERNING THE REASONS FOR RAPID FOLDING IN PROTEINS
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
1999 | Articulo |
A THERMODYNAMIC STUDY OF THE 434-REPRESSOR N-TERMINAL DOMAIN AND OF ITS COVALENTLY LINKED DIMERS.
JAVIER RUIZ SANZ
|
1999 | Articulo |
FOLDING OF A PRESSURE-DENATURED MODEL PROTEIN
JAVIER RUIZ SANZ
|
1999 | Articulo |
THERMODYNAMIC ANALYSIS OF THE STRUCTURAL STABILITY OF PHAGE 434 CRO PROTEIN
JAVIER RUIZ SANZ
|
1999 | Articulo |
A THERMODYNAMIC ANALYSIS OF A FAMILY OF SMALL GLOBULAR PROTEINS: SH3 DOMAINS
ANA ISABEL AZUAGA FORTES
|
1999 | Articulo |
Interaction between class B ß-lactamases and suicide substrates of active-site serine ß-lactamases
Maria del Carmen Hernandez Valladares
|
1999 | Articulo |
Mono- and binuclear Zn2+-ß-lactamases. Role of the conserved cysteine in the catalytic mechanism
Maria del Carmen Hernandez Valladares
|
1999 | Articulo |
Hydroxamate inhibitors of Aeromonas hydrophila AE036 metallo-ß-lactamase
Maria del Carmen Hernandez Valladares
|
1999 | Articulo |
Hydroxamate inhibitors of Aeromonas hydrophila AE036 metallo-ß-lactamase
Maria del Carmen Hernandez Valladares
|
1999 | Articulo |
A comparison of Bacillus cereus and Aeromonas hydrophila Zn-ß-lactamases
Maria del Carmen Hernandez Valladares
|
1999 | Articulo |
Analysis of the interactions between streptokinase domains and human plasminogen
FRANCISCO CONEJERO LARA, ANA ISABEL AZUAGA FORTES
|
1998 | Articulo |
STRUCTURE OF THE TRANSITION STATE IN THE FOLDING PROCESS OF HUMAN PROCARBOXYPEPTIDASE A2 ACTIVATION DOMAIN
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
1998 | Articulo |
THE DSC DATA ANALYSIS FOR SMALL, SINGLE-DOMAIN PROTEINS. APPLICATION TO THE SH3 DOMAIN
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
1998 | Articulo |
OBLIGATORY STEPS IN PROTEIN FOLDING AND THE CONFORMATIONAL DIVERSITY OF THE TRANSITION STATE
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
1998 | Articulo |
Mono- and binuclear Zn-beta-lactamase from Bacteroides fragilis: catalytic and structural roles of the zinc ions
Maria del Carmen Hernandez Valladares
|
1998 | Articulo |
NMR SOLUTION STRUCTURE OF THE 205-316 C-TERMINAL FRAGMENT OF THERMOLYSIN. EXAMPLE OF DIMERIZATION COUPLED TO PARTIAL UNFOLDING
FRANCISCO CONEJERO LARA
|
1997 | Articulo |
DIFFERENTIAL SCANNING CALORIMETRY OF THERMOLYSIN AND ITS 255-316 AND 205-316 C-TERMINAL FRAGMENTS
FRANCISCO CONEJERO LARA, ANA ISABEL AZUAGA FORTES
|
1997 | Articulo |
Zn(II) dependence of the Aeromonas hydrophila AE036 metallo-ß-lactamase activity and stability
Maria del Carmen Hernandez Valladares
|
1997 | Articulo |
THERMAL STABILITY OF THE THREE DOMAINS OF STREPTOKINASE STUDIED BY CIRCULAR DICHROISM AND NUCLEAR MAGNETIC RESONANCE
FRANCISCO CONEJERO LARA, ANA ISABEL AZUAGA FORTES
|
1996 | Articulo |
MOLECULAR CHARACTERISATION OF A THERMOACTIVE BETA-1,3-GLUCANASE FROM OERSKOVIA XANTHINEOLYTICA
FRANCISCO CONEJERO LARA
|
1996 | Articulo |
PRESENCE OF A SLOW DIMERIZATION EQUILIBRIUM ON THE THERMAL UNFOLDING OF THE 205-316 THERMOLYSIN FRAGMENT AT NEUTRAL PH
FRANCISCO CONEJERO LARA
|
1996 | Articulo |
THE DOMAIN ORGANIZATION OF STREPTOKINASE: NUCLEAR MAGNETIC RESONANCE, CIRCULAR DICHROISM, AND FUNCTIONAL CHARACTERIZATION OF PROTEOLYTIC FRAGMENTS
FRANCISCO CONEJERO LARA
|
1996 | Articulo |
SCANNING CALORIMETRY AND FOURIER-TRANSFORM INFRARED STUDIES INTO THE THERMAL STABILITY OF CLEAVED BACTERIORHODOPSIN SYSTEMS
ANA ISABEL AZUAGA FORTES
|
1996 | Articulo |
Overproduction and purification of the metallo-ß-lactamase from Aeromonas hydrophila AE036
Maria del Carmen Hernandez Valladares
|
1996 | Articulo |
THE THERMODYNAMICS OF ASSOCIATION AND UNFOLDING OF THE 205-316-C-TERMINAL FRAGMENT OF THERMOLYSIN
FRANCISCO CONEJERO LARA, ANA ISABEL AZUAGA FORTES
|
1995 | Articulo |
ESTUDIO DE LA DESNATURALIZACION TERMICA E INTERACCION CON LIGANDOS DE PROTEINAS DE BAJO PESO MOLECULAR
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
1995 | Tesis Doctoral |
A CALORIMETRIC STUDY OF THE THERMAL-STABILITY OF BARSTAR AND ITS INTERACTION WITH BARNASET
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
1995 | Articulo |
CONFORMATIONAL PATHWAY OF THE POLYPEPTIDE CHAIN OF CHYMOTRYPSIN INHIBITOR-2 GROWING FROM ITS N TERMINUS IN VITRO. PARALLELS WITH THE PROTEIN FOLDING PATHWAY
JAVIER RUIZ SANZ
|
1995 | Articulo |
FOLDING OF A NASCENT POLYPEPTIDE CHAIN IN VITRO: COOPERATIVE FORMATION OF STRUCTURE IN A PROTEIN MODULE
JAVIER RUIZ SANZ
|
1995 | Articulo |
SEARCH FOR NUCLEATION SITES IN SMALLER FRAGMENTS OF CHYMOTRYPSIN INHIBITOR2
JAVIER RUIZ SANZ
|
1995 | Articulo |
PROTEIN FRAGMENTS AS MODELS FOR EVENTS IN PROTEIN FOLDING PATHWAYS: PROTEIN ENGINEERING ANALYSIS OF THE ASSOCIATION OF TWO COMPLEMENTARY FRAGMENTS OF THE BARLEY CHYMOTRYPSIN INHIBITOR 2 (CI-2).
JAVIER RUIZ SANZ
|
1995 | Articulo |
EVIDENCE FOR A 2-STATE TRANSITION IN THE FOLDING PROCESS OF THE ACTIVATION DOMAIN OF HUMAN PROCARBOXYPEPTIDASE-A2
ANA ISABEL AZUAGA FORTES
|
1995 | Articulo |
ESTUDIO CALORIMETRICO DE LA ESTABILIDAD TERMICA DE PEQUEÑAS PROTEINAS GLOBULARES Y FRAGMENTOS
ANA ISABEL AZUAGA FORTES
|
1995 | Tesis Doctoral |
THE THERMODYNAMICS OF THE UNFOLDING OF AN ISOLATED PROTEIN SUBDOMAIN – THE 255-316-C-TERMINAL FRAGMENT OF THERMOLYSIN
FRANCISCO CONEJERO LARA
|
1994 | Articulo |
THERMODYNAMIC AND KINETIC-ANALYSIS OF THE SH3 DOMAIN OF SPECTRIN SHOWS A 2-STATE FOLDING TRANSITION
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
1994 | Articulo |
A CALORIMETRIC STUDY OF THE THERMAL-STABILITY OF BARNASE AND ITS INTERACTION WITH 3’GMP
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
1994 | Articulo |
GENERATION OF A FAMILY OF PROTEIN FRAGMENTS FOR STRUCTURE-FOLDING STUDIES.2. KINETICS OF ASSOCIATION OF THE TWO CHYMOTRYPSIN INHIBITOR-2 FRAGMENTS
JAVIER RUIZ SANZ
|
1994 | Articulo |
THE STRUCTURE OF THE TRANSITION STATE FOR THE ASSOCIATION OF TWO FRAGMENTS OF THE BARLEY CHYMOTRYPSIN INHIBITOR 2 TO GENERATE NATIVE-LIKE PROTEIN: IMPLICATIONS FOR MECHANISMS OF PROTEIN FOLDING
JAVIER RUIZ SANZ
|
1994 | Articulo |
ESTABILIDAD TERMICA DE LOS SISTEMAS PRO-CARBOXIPEPTIDASA B Y FRAGMENTOS DE TERMOLISINA. ASPECTOS CINETICOS Y TERMODINAMICOS
FRANCISCO CONEJERO LARA, JOSE MANUEL SANCHEZ RUIZ
|
1993 | Tesis Doctoral |
THE INFLUENCE OF EFFECTORS AND SUBUNIT INTERACTIONS ON ESCHERICHIA-COLI CARBAMOYL-PHOSPHATE SYNTHETASE STUDIED BY DIFFERENTIAL SCANNING CALORIMETRY
FRANCISCO CONEJERO LARA, JAVIER RUIZ SANZ
|
1993 | Articulo |
A CALORIMETRIC APPROACH TO THE KINETICS OF THE IRREVERSIBLE THERMAL-DENATURATION OF PROTEINS
FRANCISCO CONEJERO LARA, JOSE MANUEL SANCHEZ RUIZ
|
1992 | Articulo |
THE THERMAL TRANSITION IN CRUDE MYELIN PROTEOLIPID HAS A LIPID RATHER THAN PROTEIN ORIGIN
JAVIER RUIZ SANZ
|
1992 | Articulo |
THERMAL STABILITY OF BOVINE-BRAIN MYELIN MEMBRANE
JAVIER RUIZ SANZ
|
1992 | Articulo |
HEAT AND COLD DENATURATION OF BETA-LACTOGLOBULIN B
ANA ISABEL AZUAGA FORTES
|
1992 | Articulo |
DIFFERENTIAL SCANNING CALORIMETRY STUDY OF CARBOXYPEPTIDASE B, PROCARBOXYPEPTIDASE B AND ITS GLOBULAR ACTIVATION DOMAIN
FRANCISCO CONEJERO LARA, JOSE MANUEL SANCHEZ RUIZ
|
1991 | Articulo |
THE EFFECT OF ZN2+ ON THE THERMAL DENATURATION OF CARBOXYPEPTIDASE B
FRANCISCO CONEJERO LARA, JOSE MANUEL SANCHEZ RUIZ
|
1991 | Articulo |
ESTABILIDAD TERMICA DE LA MEMBRANA MIELINICA. PURIFICACION CON DETERGENTES DE SUS PROTEINAS MAYORITARIAS
JAVIER RUIZ SANZ
|
1991 | Tesis Doctoral |
SURFACTANT-INDUCED RELEASE OF LIPOSOMAL CONTENTS. A SURVEY OF METHODS AND RESULTS.
JAVIER RUIZ SANZ
|
1988 | Articulo |
lmmunological Compositions Against HIV.
FRANCISCO CONEJERO LARA
|
1900 | Patente de invención |
Improved anti-HIV immunogens
FRANCISCO CONEJERO LARA
|
1900 | Patente de invención |
CONSTRUCCIONES PROTEICAS DE HEPTA-REPETICIONES NTERMINALES (HRN) DE GP41
FRANCISCO CONEJERO LARA, SALVADOR CASARES ATIENZA
|
1900 | Patente de invención |
Biocalorimetry: differential scanning calorimetry of protein solutions
FRANCISCO CONEJERO LARA
|
1900 | Capítulo de libro |
calorimetry
JOSE CRISTOBAL MARTINEZ HERRERIAS
|
1900 | Capítulo de libro |
Imipramine for use as inhibitor of Fascin1 overexpression
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER RUIZ SANZ
|
1900 | Patente de invención |
Adecuación y aplicación al área de conocimiento de química física de una metoddología basada en las TIC¿s para la adaptación al espacio europeo de educación superior
JOSE CRISTOBAL MARTINEZ HERRERIAS, JAVIER RUIZ SANZ
|
1900 | Capítulo de libro |
Engineering beta subunit of tryptophan synthase for production of non-canonical amino acids
JAVIER MURCIANO CALLES
|
1900 | Patente de invención |
Engineered Synthase for production of Tryptophan Derivatives and Intransingent Substrates
JAVIER MURCIANO CALLES
|
1900 | Patente de invención |
COMPOSITIONS FOR THE TREATMENT OF HYPERPHENYLALANINEMIA
ANGEL LUIS PEY RODRÍGUEZ
|
1900 | Patente de invención |